Recombinant Human Tgf Beta 1 Protein-模型资源库_基因_影像分析平台

Recombinant Human Tgf Beta 1 Protein

CED, DPD1, LAP, TGF B1, TGF beta 1, tgf beta1, TGFB, TGFB1, TGFbeta, tgf-beta1

Cat No

P33538Hu00

Synonyms

CED, DPD1, LAP, TGF B1, TGF beta 1, tgf beta1, TGFB, TGFB1, TGFbeta, tgf-beta1

Uniprot

P01137

Full name

Transforming growth factor beta-1 proprotein

概述

质检展示

Recombinant human

Recombinant human TGF beta 1 (HZ-1011) inhibits IL-4 induced proliferation of the HT-2 mouse cell line. HT-2 cells are Balb/c spleen cells activated by sheep erythrocytes in the presence of IL-2. Cell number was quantitatively assessed by PrestoBlue® cell viability reagent. HT-2 cells were treated with increasing concentrations of recombinant TGF beta 1 for 72 hours. The EC50 was determined using a 4-parameter non-linear regression model. The EC50 range is 0.01-0.17 ng/mL.

Human iPSC-derived microglia

Human iPSC-derived microglia (white) residing within an in vivo brain-like organoid environment (blue) derived using HumanKine growth factors (TGF beta 1- HZ-1011, BMP4- HZ-1045, and Thrombopoietin HZ-1248).(Credits- Credit: Simon T. Schafer & Monique Pena, Technical University of Munich, Center for Organoid Systems)

Schafer & Monique Pena, Technical University of Munich

质检说明

文献引用

Yu, ShuJun. et al. Low temperature plasma protects against inflammatory agents-mediated dysfunction of theca cells via enhancing MANF expression. MOL BIOL REP. 2023 Jan;:1-13 WB ; Mouse.

产品概述

Expression: e coli.-derived, PGEX-4T

Tag: GST

Species: Homo sapiens

Molecular Mass: 12-14kDa

Purity: > 92 % as determined by SDS-PAGE

Endotoxin Level: <1.0 EU per ug of the protein as determined by the LAL method.

Activity: No tested

Sequence Description: ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS

Background: TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, and cell differentiation. TGF acts synergistically with TGFA in inducing transformation process. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB having specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling being a potent stimulator of an osteoblastic bone formation

产品性能

Yu, ShuJun. et al. Low temperature plasma protects against inflammatory agents-mediated dysfunction of theca cells via enhancing MANF expression. MOL BIOL REP. 2023 Jan;:1-13 WB ; Mouse.

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